{"id":603,"date":"2026-07-31T13:56:28","date_gmt":"2026-07-31T13:56:28","guid":{"rendered":"https:\/\/komtesz.hu\/?page_id=603"},"modified":"2026-07-31T14:25:18","modified_gmt":"2026-07-31T14:25:18","slug":"603-2","status":"publish","type":"page","link":"https:\/\/komtesz.hu\/en\/603-2\/","title":{"rendered":"Befejez\u0151d\u00f6tt az \u201eExtracellul\u00e1ris vezikul\u00e1k \u00e9s egy\u00e9b biol\u00f3giai nanor\u00e9szecsk\u00e9k automatiz\u00e1lt elv\u00e1laszt\u00e1s\u00e1ra alkalmas kromatogr\u00e1fi\u00e1s eszk\u00f6z kifejleszt\u00e9se\u201d c\u00edm\u0171 p\u00e1ly\u00e1zat 2021-1.1.4-GYORS\u00cdT\u00d3S\u00c1V-2022-00072"},"content":{"rendered":"

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AKT\u00cdV PROJEKTEK – SAJT\u00d3K\u00d6ZLEM\u00c9NY | 2026.05.31.<\/p>\n

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Befejez\u0151d\u00f6tt az
\n\u201eExtracellul\u00e1ris vezikul\u00e1k \u00e9s egy\u00e9b biol\u00f3giai nanor\u00e9szecsk\u00e9k automatiz\u00e1lt
\nelv\u00e1laszt\u00e1s\u00e1ra alkalmas kromatogr\u00e1fi\u00e1s eszk\u00f6z kifejleszt\u00e9se\u201d c\u00edm\u0171 p\u00e1ly\u00e1zat
\n2021-1.1.4-GYORS\u00cdT\u00d3S\u00c1V-2022-00072<\/h2>\n

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A KOMTESZ Kommunik\u00e1ci\u00f3s \u00e9s Technikai
\nSzolg\u00e1ltat\u00f3 Korl\u00e1tolt Felel\u0151ss\u00e9g\u0171 T\u00e1rsas\u00e1g\u201eExtracellul\u00e1ris vezikul\u00e1k \u00e9s egy\u00e9b biol\u00f3giai nanor\u00e9szecsk\u00e9k automatiz\u00e1lt elv\u00e1laszt\u00e1s\u00e1ra alkalmas kromatogr\u00e1fi\u00e1s eszk\u00f6z kifejleszt\u00e9se\u201d c\u00edmmel 176,388 milli\u00f3 forint vissza nem t\u00e9r\u00edtend\u0151 t\u00e1mogat\u00e1st nyert a Nemzeti Kutat\u00e1si, Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal \u00e1ltal meghirdetett \u201e2021-1.1.4-
\nGYORS\u00cdT\u00d3S\u00c1V\u201d k\u00f3dsz\u00e1m\u00fa, \u201eGYORS\u00cdT\u00d3S\u00c1V\u201d felh\u00edv\u00e1s\u00e1n.<\/p>\n

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A projekt 2023.03.01-\u00e9n indult, majd 2026.05.31-\u00e9n sikersen z\u00e1rult. A projekt \u00e1ltal\u00e1nos h\u00e1ttere, hogy mostanra ker\u00fclt a potenci\u00e1lis klinikai felhaszn\u00e1l\u00e1s k\u00fcsz\u00f6b\u00e9re egy \u00faj elven m\u0171k\u00f6d\u0151 diagnosztikai ir\u00e1ny. Az \u00fan. extracellul\u00e1ris vezikul\u00e1kkal (EV-kel), melyek a sejtek k\u00f6z\u00f6tti kommunik\u00e1ci\u00f3\u00e9rt felel\u0151s biol\u00f3giai nanor\u00e9szecsk\u00e9k, sz\u00e1mos r\u00e1kos megbeteged\u00e9s, sz\u00edv- \u00e9s \u00e9rrendszeri elv\u00e1ltoz\u00e1s el\u0151re jelezhet\u0151 m\u00e1r eg\u00e9szen korai st\u00e1diumban, \u00edgy a megfelel\u0151 diagn\u00f3zis fel\u00e1ll\u00edt\u00e1s\u00e1t seg\u00edtheti, illetve elker\u00fclhet\u0151v\u00e9
\nteheti komplik\u00e1lt, sz\u00e1mottev\u0151 kock\u00e1zattal j\u00e1r\u00f3, \u00e9s k\u00f6lts\u00e9ges beavatkoz\u00e1sok (pl.biopszia) alkalmaz\u00e1sa.<\/p>\n

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A fejleszt\u00e9s eredm\u00e9nyek\u00e9nt egy olyan automatiz\u00e1lhat\u00f3, kompakt diagnosztikai eszk\u00f6z protot\u00edpusa j\u00f6tt l\u00e9tre, amely alkalmas az EV-k gyors \u00e9s megb\u00edzhat\u00f3 izol\u00e1l\u00e1s\u00e1ra, valamint alapvet\u0151 jellemz\u00e9s\u00e9re. Az extracellul\u00e1ris vezikul\u00e1k a sejtek k\u00f6z\u00f6tti kommunik\u00e1ci\u00f3 fontos szerepl\u0151i, ez\u00e9rt egyre
\nnagyobb jelent\u0151s\u00e9ggel b\u00edrnak a korszer\u0171 diagnosztikai \u00e9s biomarker-kutat\u00e1sokban.<\/p>\n

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A projekt sor\u00e1n egy m\u00e9retkiz\u00e1r\u00e1sos kromatogr\u00e1fi\u00e1n (SEC) alapul\u00f3 elv\u00e1laszt\u00f3rendszert fejlesztett\u00fcnk ki, amelyet saj\u00e1t fejleszt\u00e9s\u0171 optikai detektorrendszerrel, vez\u00e9rl\u0151elektronik\u00e1val \u00e9s szoftverrel integr\u00e1ltunk. A rendszer laborat\u00f3riumi k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt sikeresen bizony\u00edtotta
\nm\u0171k\u00f6d\u0151k\u00e9pess\u00e9g\u00e9t, \u00e9s lehet\u0151v\u00e9 teszi az EV-k automatiz\u00e1lt feldolgoz\u00e1s\u00e1t, valamint fluoreszcens jel\u00f6l\u00e9sen alapul\u00f3 vizsg\u00e1lat\u00e1t is.<\/p>\n

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A technol\u00f3giai fejleszt\u00e9ssel p\u00e1rhuzamosan jelent\u0151s tudom\u00e1nyos eredm\u00e9nyek is sz\u00fclettek. A kutat\u00e1sok sor\u00e1n k\u00fcl\u00f6nb\u00f6z\u0151 eredet\u0171 EV-mint\u00e1kon dolgoztunk, \u00faj izol\u00e1l\u00e1si \u00e9s molekul\u00e1ris vizsg\u00e1lati protokollokat dolgoztunk ki, valamint igazoltuk, hogy a rendszerrel el\u0151\u00e1ll\u00edtott mint\u00e1k alkalmasak
\nRNS- \u00e9s mikroRNS-alap\u00fa biomarkerek vizsg\u00e1lat\u00e1ra. Az eredm\u00e9nyeket t\u00f6bb nemzetk\u00f6zi konferenci\u00e1n mutattuk be, \u00e9s azok tov\u00e1bbi tudom\u00e1nyos publik\u00e1ci\u00f3k, illetve kutat\u00e1si egy\u00fcttm\u0171k\u00f6d\u00e9sek alapj\u00e1ul is
\nszolg\u00e1ltak.<\/p>\n

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A fejleszt\u00e9s egyik legfontosabb eredm\u00e9nye, hogy az optimaliz\u00e1lt elj\u00e1r\u00e1s teljes\u00edtm\u00e9nye m\u00e1r megk\u00f6zel\u00edti a jelenleg sz\u00e9les k\u00f6rben alkalmazott ultracentrifug\u00e1l\u00e1ssal egybek\u00f6t\u00f6tt elv\u00e1laszt\u00e1s
\nhat\u00e9konys\u00e1g\u00e1t, ugyanakkor egyszer\u0171bb, automatiz\u00e1lhat\u00f3 \u00e9s k\u00f6lts\u00e9ghat\u00e9konyabb alternat\u00edv\u00e1t k\u00edn\u00e1l. A projekt sor\u00e1n l\u00e9trej\u00f6tt detektormodul \u00f6n\u00e1ll\u00f3 term\u00e9kk\u00e9nt is hasznos\u00edthat\u00f3, emellett a kutat\u00e1s
\neredm\u00e9nyek\u00e9nt \u00faj, \u00e1llati eredet\u0171 extracellul\u00e1ris vezikula-mint\u00e1k el\u0151\u00e1ll\u00edt\u00e1sa is megval\u00f3sult, amelyek tov\u00e1bbi kutat\u00e1si \u00e9s ipari felhaszn\u00e1l\u00e1sra is alkalmasak.<\/p>\n

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A projekt eredm\u00e9nyek\u00e9nt olyan magas technol\u00f3giai k\u00e9sz\u00fclts\u00e9g\u0171 protot\u00edpus k\u00e9sz\u00fclt el, amely megalapozza a technol\u00f3gia ipari hasznos\u00edt\u00e1s\u00e1t \u00e9s piaci bevezet\u00e9s\u00e9t. A fejleszt\u00e9s hozz\u00e1j\u00e1rulhat a korszer\u0171 diagnosztikai m\u00f3dszerek fejl\u0151d\u00e9s\u00e9hez, valamint hosszabb t\u00e1von el\u0151seg\u00edtheti a szem\u00e9lyre szabott orvosl\u00e1s \u00e9s a biomarker-alap\u00fa laborat\u00f3riumi diagnosztika elterjed\u00e9s\u00e9t.<\/p>\n

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\n

G\u00f6d\u00f6ll\u0151, 2026.05.31.\u00a0<\/span><\/p>\n<\/div>\n

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AKT\u00cdV PROJEKTEK – SAJT\u00d3K\u00d6ZLEM\u00c9NY | 2026.05.31.Befejez\u0151d\u00f6tt az \u201eExtracellul\u00e1ris vezikul\u00e1k \u00e9s egy\u00e9b biol\u00f3giai nanor\u00e9szecsk\u00e9k automatiz\u00e1lt elv\u00e1laszt\u00e1s\u00e1ra alkalmas kromatogr\u00e1fi\u00e1s eszk\u00f6z kifejleszt\u00e9se\u201d c\u00edm\u0171 p\u00e1ly\u00e1zat 2021-1.1.4-GYORS\u00cdT\u00d3S\u00c1V-2022-00072A KOMTESZ Kommunik\u00e1ci\u00f3s \u00e9s Technikai Szolg\u00e1ltat\u00f3 Korl\u00e1tolt Felel\u0151ss\u00e9g\u0171 T\u00e1rsas\u00e1g\u201eExtracellul\u00e1ris vezikul\u00e1k \u00e9s egy\u00e9b biol\u00f3giai nanor\u00e9szecsk\u00e9k automatiz\u00e1lt elv\u00e1laszt\u00e1s\u00e1ra alkalmas kromatogr\u00e1fi\u00e1s eszk\u00f6z kifejleszt\u00e9se\u201d c\u00edmmel 176,388 milli\u00f3 forint vissza nem t\u00e9r\u00edtend\u0151 t\u00e1mogat\u00e1st nyert a Nemzeti Kutat\u00e1si, Fejleszt\u00e9si \u00e9s […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-603","page","type-page","status-publish","hentry"],"yoast_head":"\nBefejez\u0151d\u00f6tt az \u201eExtracellul\u00e1ris vezikul\u00e1k \u00e9s egy\u00e9b biol\u00f3giai nanor\u00e9szecsk\u00e9k automatiz\u00e1lt elv\u00e1laszt\u00e1s\u00e1ra alkalmas kromatogr\u00e1fi\u00e1s eszk\u00f6z kifejleszt\u00e9se\u201d c\u00edm\u0171 p\u00e1ly\u00e1zat 2021-1.1.4-GYORS\u00cdT\u00d3S\u00c1V-2022-00072 - 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